A novel monoclonal antibody therapy cuts LDL cholesterol by half in a high-risk patient population

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol—the so-called “bad” cholesterol—by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found. Results from the study sponsored by Regeneron, are being […]

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New ALS guideline establishes national standard for managing neurodegenerative disease

The first Canadian guideline for the care and management of patients with amyotrophic lateral sclerosis (ALS)—Lou Gehrig’s disease—recommends a patient-focused approach, with attention to holistic and emotional aspects of well-being. The guideline, published in CMAJ (Canadian Medical Association Journal), is intended for ALS clinicians, allied health professionals and primary care providers, and contains an easy-to-reference […]

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Study finds antibiotics before age 2 associated with childhood health issues

In a retrospective case study, Mayo Clinic researchers have found that antibiotics administered to children younger than 2 are associated with several ongoing illnesses or conditions, ranging from allergies to obesity. The findings appear in Mayo Clinic Proceedings. Using health record data from the Rochester Epidemiology Project, a population-based research collaboration in Minnesota and Wisconsin, […]

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